Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 11/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16592450 | 1.00 | APP (0.74) | APPNPC1RAB9AKDM4EGAA | |
| SCHEMBL8854378 | 0.86 | CYP1A1 (0.65) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL22010235 | 0.86 | CYP1A1 (0.65) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL8854590 | 0.82 | APP (0.74) | APPNPC1RAB9AGAAMAPT | |
| SCHEMBL5720643 | 0.82 | APP (0.85) | APPCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL5720639 | 0.82 | APP (0.85) | APPCYP1A1CYP1A2CYP1B1TUBB4A | |
| SCHEMBL9189630 | 0.80 | TUBB4A (0.65) | NPC1RAB9AKDM4EGAAMAPT | |
| SCHEMBL9189623 | 0.80 | TUBB4A (0.65) | NPC1RAB9AKDM4EGAAMAPT | |
| SCHEMBL21005800 | 0.80 | TUBB4A (0.65) | NPC1RAB9AKDM4EGAAMAPT | |
| SCHEMBL30842581 | 0.80 | APP (0.48) | APPNPC1RAB9AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2853565-A1 | Glutamate receptor photomodulators | Consejo Superior De Investigaciones Científicas (ES) | 2015-04-01 | — | — | EP | disclosed |