SCHEMBL22010235

SCHEMBL22010235

COc1ccc(/C=C/c2ccccn2)cc1OC

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 6/20 0.65
CYP1B1 Q16678 5/20 0.65
CYP1A2 P05177 3/20 0.65
MAPT P10636 2/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
GLA P06280 1/20 0.61
NQO2 P16083 3/20 0.59
CYP19A1 P11511 2/20 0.59
NPC1 O15118 1/20 0.56
GAA P10253 1/20 0.56
RAB9A P51151 1/20 0.56
GFER P55789 1/20 0.56
TUBB4A P04350 1/20 0.56
TUBB P07437 1/20 0.56
TUBA3C P0DPH7 1/20 0.56
TUBA1B P68363 1/20 0.56
TUBA4A P68366 1/20 0.56
TUBB4B P68371 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8854378 1.00 CYP1A1 (0.65) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL709522 0.91 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL709523 0.91 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL16592450 0.86 APP (0.74) CYP1A1CYP1B1CYP1A2MAPTGLA
SCHEMBL16592452 0.86 APP (0.74) CYP1A1CYP1B1CYP1A2MAPTGLA
SCHEMBL8854590 0.86 APP (0.74) MAPTNPC1GAARAB9ANFE2L2
SCHEMBL1388244 0.84 PDE4A (0.54) CYP1A1CYP1B1CYP1A2ALDH1A1GLA
SCHEMBL1388242 0.84 PDE4A (0.54) CYP1A1CYP1B1CYP1A2ALDH1A1GLA
SCHEMBL9189623 0.84 TUBB4A (0.65) CYP1A1CYP1B1CYP1A2MAPTALDH1A1
SCHEMBL21005800 0.84 TUBB4A (0.65) CYP1A1CYP1B1CYP1A2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3041904-B1 STYRYL SULFIDE DYES BASF SE (DE) 2020-05-20 EP disclosed