SCHEMBL1659303

SCHEMBL1659303

CC(C)(C[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c1ccccc1)O[Sn](CC(C)(C)c1ccccc1)(CC(C)(C)c1ccccc1)CC(C)(C)c1ccccc1)c1ccccc1.O=P(O)(O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 7/20 0.40
ITPR1 Q14643 4/20 0.40
ITPR2 Q14571 3/20 0.40
PDPK1 O15530 2/20 0.40
MTOR P42345 1/20 0.40
INPP5A Q14642 2/20 0.39
SMPD1 P17405 1/20 0.38
INPPL1 O15357 1/20 0.36
AKT1 P31749 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inositol SCHEMBL8443504 0.89 TAAR1 (0.37)
SCHEMBL2768375 0.89 FUCA1 (0.40)
Inositol SCHEMBL3079466 0.85 TAAR1 (0.42)
Phosphoric Acid SCHEMBL6689741 0.83 TAAR1 (0.41)
Inositol SCHEMBL8441010 0.81 TAAR1 (0.37)
SCHEMBL23850856 0.80 ALDH1A1 (0.34)
Phosphoric Acid SCHEMBL5665038 0.77 TAAR1 (0.41)
SCHEMBL55578 0.77 TAAR1 (0.50)
Iodide SCHEMBL6625841 0.75 TAAR1 (0.48)
Phosphine SCHEMBL9467574 0.75 TAAR1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230048403-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF ALZHEIMER'S DISEASE USING PHYTIC ACID AND PHYTATE TO REDUCE AMYLOID BETA PLAQUE AND TAU PROTEIN SABIN ROBERT (US) 2023-02-16 US disclosed
US-20210038618-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF ALZHEIMER'S DISEASE USING PHYTIC ACID AND PHYTATE TO REDUCE AMYLOID BETA PLAQUE AND TAU PROTEIN SABIN ROBERT (US) 2021-02-11 US disclosed
US-20200078380-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF ALZHEIMER'S DISEASE USING PHYTIC ACID AND PHYTATE TO REDUCE AMYLOID BETA PLAQUE AND TAU PROTEIN SABIN ROBERT (US) 2020-03-12 US disclosed
CN-104313589-A Micro emulsion type metal anti-rusting liquid and preparation method thereof SUZHOU CHANGSHENG ELECTROMECHANICAL CO LTD 2015-01-28 CN disclosed
US-8541036-B2 Synergetic effect of the phytase combination on the hydrolysis of phytic acid ADISSEO FRANCE S.A.S. (FR) 2013-09-24 US disclosed
WO-2011119136-A1 PROPHYLACTIC AND THERAPEUTIC TREATMENT OF NEURO-DEGENERATIVE DISEASES AND PROTEIN AGGREGATION DISEASES SABIN ROBERT (US) 2011-09-29 WO disclosed
CN-101263226-B Debaryomyces carinii phytase ADISSEO FRANCE SAS 2011-08-17 CN disclosed
US-20110091440-A1 Prophylactic and therapeutic treatment of neuro-degenerative diseases and protein aggregation diseases SABIN ROBERT 2011-04-21 US disclosed
US-20100278965-A1 Synergetic Effect of the Phytase Combination on the Hydrolysis of Phytic Acid ADISSEO FRANCE S.A.S. (FR) 2010-11-04 US disclosed
US-20100249073-A1 Prophylactic and therapeutic treatment of Alzheimer's disease using phytic acid and phytate to reduce amyloid beta plaque and tau protein SABIN ROBERT 2010-09-30 US disclosed
CN-101263226-A Debaryomyces castellii phytase ADISSEO FRANCE SAS (FR) 2008-09-10 CN disclosed
EP-1910531-A1 SYNERGISTIC EFFECT OF THE COMBINATION OF PHYTASES ON HYDROLYSIS OF PHYTIC ACID Adisseo France S.A.S. (FR) 2008-04-16 EP disclosed
WO-2007006952-A1 SYNERGISTIC EFFECT OF THE COMBINATION OF PHYTASES ON HYDROLYSIS OF PHYTIC ACID ADISSEO FRANCE S.A.S. (FR) 2007-01-18 WO disclosed
US-5217959-A Method of treating multiple sclerosis with phytic acid JARIWALLA, RAXIT 1993-06-08 US disclosed
US-5206226-A Method of treatment of Parkinsons's disease using phytic acid SABIN ROBERT (US) 1993-04-27 US disclosed
US-5112814-A Method of treatment of Parkinson's disease using phytic acid SABIN ROBERT (US) 1992-05-12 US disclosed
EP-0420428-A2 Mehod of treatment of rheumatoid arthritis using phytic acid Sabin, Robert (US) 1991-04-03 EP disclosed
US-4952396-A OR SALTS OR HYDROLYZATES; ORAL ADMINISTRATION LINUS PAULING INSTITUTE OF SCIENCE & MEDICINE (US) 1990-08-28 US disclosed
US-4847082-A Method of treatment of Alzheimer's disease using phytic acid Sabin, Robert (US) 1989-07-11 US disclosed
US-4758430-A Method of treatment of Alzheimer's disease using phytic acid SABIN ROBERT (US) 1988-07-19 US disclosed