SCHEMBL16593271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16593228	0.82	MAPK1 (0.50)	HTTCYP11B1CYP11B2SMN1; SMN2CHRM1
	SCHEMBL16593230	0.81	POLB (0.45)	LMNAHTTSMN1; SMN2CHRM1KDM4E
	SCHEMBL21043119	0.81	ALDH1A1 (0.42)	GABRA1GABRA5LMNAHTTSMN1; SMN2
	SCHEMBL16628260	0.80	CHRM1 (0.46)	GABRA1GABRA5CHRM1
	SCHEMBL22001177	0.80	POLB (0.48)	GABRA1GABRA5LMNAHTTCHRM1
	SCHEMBL16593480	0.78	CHRM1 (0.53)	CHRM1
	SCHEMBL16593257	0.77	POLB (0.42)	LMNAHTTCYP11B1CYP11B2SMN1; SMN2
	SCHEMBL16593586	0.77	TLR7 (0.38)	LMNAHTTCYP11B1CYP11B2SMN1; SMN2
	SCHEMBL16593312	0.75	CHRM1 (0.56)	CHRM1KDM4EALDH1A1
	SCHEMBL19779978	0.74	CHRM1 (0.42)	HTTCYP11B1CYP11B2SMN1; SMN2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.