Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 15/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE6D | O43924 | 2/20 | 0.41 |
| ▸ | PDE6A | P16499 | 2/20 | 0.41 |
| ▸ | PDE6G | P18545 | 2/20 | 0.41 |
| ▸ | PDE6B | P35913 | 2/20 | 0.41 |
| ▸ | PDE6C | P51160 | 2/20 | 0.41 |
| ▸ | PDE6H | Q13956 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22001177 | 0.90 | POLB (0.48) | CHRM1CNR1CNR2PDE6DPDE6A | |
| SCHEMBL18011014 | 0.84 | CHRM1 (0.43) | CHRM1CNR1CNR2PDE6DPDE6A | |
| SCHEMBL16628259 | 0.84 | ADRA1D (0.50) | CHRM1CNR2ADRA1D | |
| SCHEMBL16628263 | 0.82 | POLB (0.56) | CHRM1CNR2 | |
| SCHEMBL21043119 | 0.81 | ALDH1A1 (0.42) | CHRM1GABRA1GABRA5 | |
| SCHEMBL16628329 | 0.81 | CHRM1 (0.44) | CHRM1PDE6DPDE6APDE6GPDE6B | |
| SCHEMBL22001755 | 0.80 | CHRM1 (0.63) | CHRM1 | |
| SCHEMBL16593271 | 0.80 | GABRA1 (0.41) | CHRM1GABRA1GABRA5 | |
| SCHEMBL22001753 | 0.80 | POLB (0.53) | CHRM1 | |
| SCHEMBL16628265 | 0.80 | ADRA1D (0.41) | CHRM1CNR1CNR2PDE6DPDE6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049574-A1 | 4-AZAINDOLE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-09 | — | — | WO | disclosed |