Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16604821 | 0.85 | CYP2A6 (0.33) | POLBKDM4ESMN1; SMN2 | |
| SCHEMBL16609060 | 0.85 | POLB (0.34) | POLB | |
| SCHEMBL16609141 | 0.84 | POLB (0.48) | POLBKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL16593840 | 0.83 | POLB (0.48) | POLBKDM4EMET | |
| SCHEMBL29431598 | 0.81 | POLB (0.52) | POLBCASP3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14677239 | 0.81 | POLB (0.52) | POLBCASP3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16593676 | 0.81 | POLB (0.42) | POLBCASP3KDM4EALDH1A1GAA | |
| SCHEMBL16594408 | 0.81 | CASP3 (0.46) | POLBCASP3KDM4EALDH1A1GAA | |
| SCHEMBL16593966 | 0.81 | POLB (0.45) | POLBKDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL15411967 | 0.81 | POLB (0.49) | POLBKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2857396-B1 | FUSED HETEROCYCLIC COMPOUNDS FOR PEST CONTROL | SUMITOMO CHEMICAL CO (JP) | 2018-11-21 | — | — | EP | disclosed |
| US-9120792-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| US-9120792-B2 | Fused heterocyclic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-09-01 | — | — | US | disclosed |
| EP-2857396-A1 | FUSED HETEROCYCLIC COMPOUND | Sumitomo Chemical Co., Ltd (JP) | 2015-04-08 | — | — | EP | disclosed |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-02 | — | — | US | disclosed |
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150094329-A1 | FUSED HETEROCYCLIC COMPOUND | CYC1, H1-0, H1-3 | POLB 4498/4885CASP3 256/4885KDM4E 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.