SCHEMBL16609060

SCHEMBL16609060

CCSc1ccsc1-c1nc2cc(SC(F)(F)F)cnc2n1C

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16593940 0.85 POLB (0.48) POLB
SCHEMBL16593718 0.85 POLB (0.35) POLB
SCHEMBL16604821 0.84 CYP2A6 (0.33) POLB
SCHEMBL16594133 0.84 POLB (0.36) POLB
SCHEMBL16593788 0.83 CASP3 (0.34) POLB
SCHEMBL16609062 0.83 POLB (0.33) POLB
SCHEMBL10280726 0.81 ALOX5AP (0.35) POLB
SCHEMBL16667060 0.81 POLB (0.35) POLB
SCHEMBL14676338 0.80 POLB (0.34) POLB
SCHEMBL29431636 0.80 POLB (0.34) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120792-B2 Fused heterocyclic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-09-01 — — US disclosed
US-20150094329-A1 FUSED HETEROCYCLIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-04-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094329-A1 FUSED HETEROCYCLIC COMPOUND CYC1, H1-0, H1-3 POLB 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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