Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 3/20 | 0.45 |
| ▸ | NCF1 | P14598 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22261686 | 1.00 | KDM4E (0.56) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL21184479 | 1.00 | KDM4E (0.56) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL21184540 | 0.84 | KDM4E (0.43) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL22261769 | 0.84 | KDM4E (0.43) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL22261767 | 0.84 | KDM4E (0.43) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL12308438 | 0.81 | KDM4E (0.49) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL25753060 | 0.81 | KDM4E (0.49) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL16594734 | 0.81 | CYP1A2 (0.53) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL16594921 | 0.81 | CYP1A2 (0.53) | KDM4EMAPK1TDP1RAB9ANPC1 | |
| SCHEMBL25753059 | 0.81 | KDM4E (0.49) | KDM4EMAPK1TDP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052465-B1 | POLYFUNCTIONALIZED POLYETHYLENE AND POLYPROPYLENE GLYCOL USEFUL AS TRACERS | RESMAN AS (NO) | 2020-07-29 | — | — | EP | claimed |
| US-10364217-B2 | Chemical compounds | RESMAN AS (NO) | 2019-07-30 | — | — | US | claimed |
| EP-3052465-A1 | CHEMICAL COMPOUNDS | Resman AS (NO) | 2016-08-10 | — | — | EP | claimed |
| US-20160214930-A1 | CHEMICAL COMPOUNDS | RESMAN AS (NO) | 2016-07-28 | — | — | US | claimed |
| WO-2015047105-A1 | CHEMICAL COMPOUNDS | RESMAN AS (NO) | 2015-04-02 | — | — | WO | claimed |
| US-20150094240-A1 | CHEMICAL COMPOUNDS | RESMAN AS (NO) | 2015-04-02 | — | — | US | claimed |
| EP-3052465-B1 | POLYFUNCTIONALIZED POLYETHYLENE AND POLYPROPYLENE GLYCOL USEFUL AS TRACERS | RESMAN AS (NO) | 2020-07-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160214930-A1 | CHEMICAL COMPOUNDS | PTGES, PTGIS, PTGFR | KDM4E 4601/4885MAPK1 2127/4885TDP1 2958/4885 |
| US-20150094240-A1 | CHEMICAL COMPOUNDS | PTGES, PTGIS, PTGFR | KDM4E 4601/4885MAPK1 2127/4885TDP1 2958/4885 |
| US-10364217-B2 | Chemical compounds | PTGES, PTGIS, PTGFR | KDM4E 4601/4885MAPK1 2127/4885TDP1 2958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.