Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595141 | 0.87 | LMNA (0.32) | LMNA | |
| SCHEMBL277289 | 0.74 | LMNA (0.33) | TAS1R3TAS1R1LMNA | |
| SCHEMBL20632266 | 0.73 | TSHR (0.36) | TAS1R3TAS1R1LMNA | |
| SCHEMBL2058301 | 0.73 | TSHR (0.36) | TAS1R3TAS1R1LMNA | |
| SCHEMBL16595155 | 0.71 | — | — | |
| SCHEMBL10549529 | 0.70 | — | — | |
| SCHEMBL22157511 | 0.69 | — | — | |
| SCHEMBL6696607 | 0.68 | — | — | |
| SCHEMBL724588 | 0.68 | — | — | |
| SCHEMBL18576568 | 0.67 | SLC6A4 (0.38) | TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015039612-A1 | COMPOUND INHIBITING KINASE ACTIVITIES OF BTK AND/OR JAK3 | 北京韩美药品有限公司 | 2015-03-26 | — | — | WO | disclosed |