Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595170 | 0.87 | TAS1R3 (0.37) | LMNA | |
| SCHEMBL16595155 | 0.78 | — | — | |
| SCHEMBL10549529 | 0.76 | — | — | |
| SCHEMBL6696607 | 0.74 | — | — | |
| SCHEMBL724588 | 0.74 | — | — | |
| SCHEMBL11466995 | 0.72 | TGFBR1 (0.32) | KDM4ESMN1; SMN2 | |
| SCHEMBL276412 | 0.67 | LMNA (0.40) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL5698964 | 0.67 | LMNA (0.38) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL1199681 | 0.67 | — | — | |
| SCHEMBL4058497 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015039612-A1 | COMPOUND INHIBITING KINASE ACTIVITIES OF BTK AND/OR JAK3 | 北京韩美药品有限公司 | 2015-03-26 | — | — | WO | disclosed |