Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15305802 | 0.85 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1 | |
| SCHEMBL9750838 | 0.79 | TSHR (0.45) | TSHRTDP1ALDH1A1 | |
| SCHEMBL4546723 | 0.79 | TSHR (0.45) | TSHRTDP1ALDH1A1 | |
| SCHEMBL6673656 | 0.77 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| SCHEMBL12240844 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL27895926 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL21587465 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL21276482 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1 | |
| SCHEMBL19112220 | 0.74 | TSHR (0.30) | TSHRTDP1 | |
| SCHEMBL19389597 | 0.72 | ALDH1A1 (0.39) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745334-B2 | Cytotoxic-drug delivering molecules targeting HIV (CDM-Hs), cytotoxic activity against the human immunodeficiency virus and methods of use | YALE UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
| US-20150087609-A1 | CYTOTOXIC-DRUG DELIVERING MOLECULES TARGETING HIV (CDM-HS), CYTOTOXIC ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USE | YALE UNIVERSITY | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087609-A1 | CYTOTOXIC-DRUG DELIVERING MOLECULES TARGETING HIV (CDM-HS), CYTOTOXIC ACTIVITY AGAINST THE HUMAN IMMUNODEFICIENCY VIRUS AND METHODS OF USE | CD4, HAVCR2, CD74 | TSHR 4086/4885TDP1 4686/4885ALDH1A1 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.