Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118929 | 1.00 | ADRB2 (0.71) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL28582068 | 1.00 | ADRB2 (0.71) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL28435051 | 0.98 | ADRB2 (0.69) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL28435050 | 0.98 | ADRB2 (0.69) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL28662709 | 0.98 | ADRB2 (0.69) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL1405554 | 0.98 | ADRB2 (0.69) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL10720145 | 0.89 | ADRB2 (0.77) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL9543386 | 0.86 | ADRB2 (0.73) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL4467889 | 0.86 | ADRB2 (0.73) | ADRB2KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL4467885 | 0.86 | ADRB2 (0.73) | ADRB2KDM4EGAASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109456277-B | Preparation method of mirabegron | 安徽省庆云医药股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-109651290-B | Preparation method of mirabegron | 安徽省庆云医药股份有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-109651290-A | A kind of preparation method of Mirabegron | 安徽省庆云医药股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-109456277-A | A kind of preparation method of Mirabegron | 安徽省庆云医药股份有限公司 | 2019-03-12 | — | — | CN | claimed |
| EP-3177589-B1 | METHOD FOR THE SYNTHESIS OF MIRABEGRON AND ITS DERIVATIVES | INTERQUIM SA (ES) | 2018-06-20 | — | — | EP | claimed |
| CN-105198830-A | Mirabegron preparation method | UNIV HENAN NORMAL | 2015-12-30 | — | — | CN | claimed |
| CN-119639838-A | Preparation method of mirabegron intermediate | 广东东阳光药业股份有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-113816864-B | Preparation method of (R) -2-hydroxy-N- [2- (4-aminophenyl) ethyl ] -2-phenethylamine | 南京正大天晴制药有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-109456277-B | Preparation method of mirabegron | 安徽省庆云医药股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-109456277-B | Preparation method of mirabegron | 安徽省庆云医药股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-110869008-B | Pharmaceutical preparation and process for its preparation | 大熊制药株式会社 | 2022-04-19 | — | — | CN | disclosed |
| CN-110862359-B | Synthesis method of mirabegron | 苏州永健生物医药有限公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-109651290-B | Preparation method of mirabegron | 安徽省庆云医药股份有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-105481705-A | Preparation and application of (R)-2-[[2-(4-aminophenyl)ethyl]amino]-1-phenylethyl alcohol | NANJING HEALTHNICE MEDICAL TECH CO LTD | 2016-04-13 | — | — | CN | disclosed |
| WO-2016024284-A2 | A PROCESS FOR THE PREPARATION OF MIRABEGRON AND ITS INTERMEDIATES | WANBURY LTD. (IN) | 2016-02-18 | — | — | WO | disclosed |
| WO-2016020440-A1 | METHOD FOR THE SYNTHESIS OF MIRABEGRON AND ITS DERIVATIVES | INTERQUIM, S.A. (ES) | 2016-02-11 | — | — | WO | disclosed |
| CN-105198830-A | Mirabegron preparation method | UNIV HENAN NORMAL | 2015-12-30 | — | — | CN | disclosed |
| WO-2015044965-A4 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |
| WO-2015044965-A1 | A PROCESS FOR PREPARATION OF MIRABEGRON AND ALPHA CRYSTALLINE FORM THEREOF | MEGAFINE PHARMA (P) LTD. (IN) | 2015-04-02 | — | — | WO | disclosed |