Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390844 | 0.95 | HSD17B10 (0.70) | MAPTHSD17B10POLBCYP1A2CYP2C19 | |
| SCHEMBL12308327 | 0.90 | HSD17B10 (0.63) | MAPTHSD17B10POLBCYP1A2CYP2C19 | |
| SCHEMBL12875982 | 0.88 | RAB9A (0.75) | MAPTHSD17B10POLBL3MBTL1TSHR | |
| SCHEMBL17278343 | 0.85 | HSD17B10 (0.68) | MAPTHSD17B10POLBCYP1A2CYP2C19 | |
| SCHEMBL23818003 | 0.84 | HSD17B10 (0.67) | MAPTHSD17B10POLBCYP1A2CYP2C19 | |
| SCHEMBL22271624 | 0.83 | MAPT (1.00) | MAPTPOLBRECQLBLML3MBTL1 | |
| SCHEMBL16784224 | 0.81 | HSD17B10 (0.67) | MAPTHSD17B10POLBRECQLBLM | |
| SCHEMBL4914872 | 0.81 | MAPT (0.67) | MAPTHSD17B10POLBL3MBTL1TSHR | |
| SCHEMBL14499419 | 0.80 | MAPT (0.72) | MAPTHSD17B10POLBRECQLBLM | |
| SCHEMBL14499420 | 0.80 | MAPT (0.72) | MAPTHSD17B10POLBRECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150086501-A1 | POLYMERS FUNCTIONALIZED WITH ION-SPECIFIC RECOGNITION ELEMENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150086501-A1 | POLYMERS FUNCTIONALIZED WITH ION-SPECIFIC RECOGNITION ELEMENTS | PUF60, PCBP1, ALG1 | MAPT 3016/4885HSD17B10 4608/4885POLB 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.