Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.64 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.59 |
| ▸ | RELA | Q04206 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12875982 | 0.92 | RAB9A (0.75) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11062952 | 0.85 | MAPT (0.67) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13390844 | 0.84 | HSD17B10 (0.70) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL29328206 | 0.82 | TAS1R3 (0.69) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL12308327 | 0.82 | HSD17B10 (0.63) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL16596165 | 0.81 | MAPT (0.71) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5923997 | 0.79 | NPC1 (0.69) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL1742667 | 0.79 | CYP1A2 (0.81) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19449475 | 0.79 | NPC1 (0.73) | MAPTRAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL179084 | 0.79 | NPC1 (0.79) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | claimed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | claimed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | claimed |
| US-20080112899-A1 | Carboxamides and Their Use | GIVAUDAN S.A. (CH) | 2008-05-15 | — | — | US | disclosed |
| EP-1814845-A1 | CARBOXAMIDES AND THEIR USE | Givaudan SA (CH) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006056087-A1 | CARBOXAMIDES AND THEIR USE | GIVAUDAN SA (CH) | 2006-06-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080112899-A1 | Carboxamides and Their Use | NQO2, CBR3, COX4I1 | MAPT 1874/4885RAB9A 3591/4885SMN1; SMN2 2027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.