Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
| ▸ | PTPN12 | Q05209 | 2/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16596256 | 0.90 | ENPP2 (0.61) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL17958360 | 0.90 | ENPP2 (0.61) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL17971218 | 0.87 | ENPP2 (0.49) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL17958356 | 0.84 | ENPP2 (0.59) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL17958357 | 0.84 | ENPP2 (0.59) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL16596300 | 0.82 | ENPP2 (0.54) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL16586424 | 0.81 | ENPP2 (0.69) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL16586422 | 0.81 | ENPP2 (0.69) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL16596433 | 0.81 | ENPP2 (0.51) | ENPP2MAPTAPPSNCAKMT2A | |
| SCHEMBL16596431 | 0.80 | ENPP2 (0.50) | ENPP2MAPTAPPSNCAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015042053-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-8952016-B2 | Substituted xanthine derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2015-02-10 | — | — | US | disclosed |