Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 4/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17958312 | 1.00 | ENPP2 (0.67) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL16596272 | 0.92 | ENPP2 (0.56) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17971257 | 0.90 | ENPP2 (0.57) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17958322 | 0.86 | ENPP2 (0.69) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL16596276 | 0.86 | ENPP2 (0.69) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL16596242 | 0.84 | ENPP2 (0.69) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17968553 | 0.84 | ENPP2 (0.77) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17958334 | 0.84 | ENPP2 (0.69) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17968551 | 0.84 | ENPP2 (0.77) | ENPP2KMT2AAPPPTPN7PTPN12 | |
| SCHEMBL17971233 | 0.82 | ENPP2 (0.47) | ENPP2APPALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-9714240-B2 | Vinyl autotaxin inhibitor compounds | PHARMAKEA, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-04 | — | — | US | disclosed |
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | DF 2024 IP ACQUISITION, LLC | 2016-08-04 | — | — | US | disclosed |
| WO-2015042053-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | PHARMAKEA, INC. (US) | 2015-03-26 | — | — | WO | disclosed |
| US-8952016-B2 | Substituted xanthine derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2015-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222000-A1 | VINYL AUTOTAXIN INHIBITOR COMPOUNDS | ENPP2, SERPINB1, SERPINB10 | ENPP2 1/4885KMT2A 1696/4885APP 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.