Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15711264 | 0.76 | CYP11B1 (0.49) | TSHR | |
| SCHEMBL16598261 | 0.75 | HRH3 (0.44) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL16598178 | 0.71 | HRH3 (0.44) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL6648949 | 0.71 | HPGD (0.38) | LMNA | |
| SCHEMBL41191 | 0.70 | L3MBTL1 (0.59) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL29830938 | 0.70 | L3MBTL1 (0.59) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 | |
| SCHEMBL15034180 | 0.69 | MAPT (0.49) | LMNAALDH1A1KDM4EMAPTBRD4 | |
| SCHEMBL10513619 | 0.68 | NPC1 (0.46) | LMNAALDH1A1ALOX15L3MBTL1TSHR | |
| SCHEMBL4938201 | 0.68 | L3MBTL1 (0.57) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10884973 | 0.68 | L3MBTL1 (0.57) | LMNATAAR1ALDH1A1ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015048503-A2 | N-ARYLMETHYL SULFONAMIDE NEGATIVE MODULATORS OF NR2A | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |