Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 2/20 | 0.45 |
| ▸ | CCR5 | P51681 | 2/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13610027 | 0.89 | KDM4E (0.55) | NPC1TP53SMN1; SMN2TSHRKDM4E | |
| SCHEMBL13184344 | 0.84 | KDM4E (0.52) | NPC1TP53SMN1; SMN2TSHRKDM4E | |
| SCHEMBL2160894 | 0.81 | KDM4E (0.45) | NPC1TP53SMN1; SMN2TSHRKDM4E | |
| SCHEMBL21241337 | 0.80 | CCR1 (0.57) | KDM4EPOLBCCR1CCR5CCR8 | |
| SCHEMBL16200268 | 0.77 | CTSA (0.35) | NPC1SMN1; SMN2KDM4ERAB9AMAPT | |
| SCHEMBL14822776 | 0.77 | PTGS2 (0.54) | NPC1SMN1; SMN2KDM4ECYP1A2RAB9A | |
| SCHEMBL24419756 | 0.76 | IDH1 (0.43) | NPC1SMN1; SMN2KDM4ECCR1CCR5 | |
| SCHEMBL2013031 | 0.76 | LMNA (0.47) | NPC1KDM4ELMNAPOLBP4HTM | |
| SCHEMBL22619641 | 0.74 | LMNA (0.46) | NPC1KDM4ELMNAPOLBP4HTM | |
| Lithium SCHEMBL31039825 | 0.74 | LMNA (0.46) | NPC1KDM4ELMNAPOLBP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10879470-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-12-29 | — | — | US | disclosed |
| US-10633585-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2020-04-28 | — | — | US | disclosed |
| US-20170321118-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2017-11-09 | — | — | US | disclosed |
| US-20170170401-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-15 | — | — | US | disclosed |
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |
| US-4881965-A | CONTROLLING WILD OATS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0318602-A1 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| CN-86100911-A | The preparation method of pyrazoles sulfone amide derivative and the weedicide that contains this kind derivative | — | 1986-09-24 | — | — | CN | disclosed |
| EP-0189069-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170321118-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, MCM4 | NPC1 2401/4885TP53 2434/4885SMN1; SMN2 4751/4885 |
| US-10633585-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CRY2, MCM4 | NPC1 2401/4885TP53 2434/4885SMN1; SMN2 4751/4885 |
| US-10879470-B2 | Condensed cyclic compound and organic light-emitting device including the same | CRY1, CRY2, CCNT1 | NPC1 1419/4885TP53 2434/4885SMN1; SMN2 1380/4885 |
| US-20170170401-A1 | CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, CRY2, MCM4 | NPC1 2344/4885TP53 1424/4885SMN1; SMN2 2037/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.