SCHEMBL1660005

SCHEMBL1660005

CC(CCO)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 4/20 0.49
LMNA P02545 2/20 0.45
TRPA1 O75762 1/20 0.43
TYR P14679 1/20 0.41
RIPK1 Q13546 1/20 0.41
NR1H4 Q96RI1 2/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
ATM Q13315 1/20 0.36
GPR35 Q9HC97 1/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13557448 0.83 GRIA4 (0.51) GRIA4LMNATRPA1TYRNR1H4
SCHEMBL19937891 0.82 GRIA4 (0.43) GRIA4LMNATYRNR1H4AKR1C3
SCHEMBL6948298 0.81 LMNA (0.43) GRIA4LMNATYRNR1H4AKR1C3
SCHEMBL6940717 0.81 LMNA (0.43) GRIA4LMNATYRNR1H4AKR1C3
SCHEMBL3187891 0.80 LMNA (0.45) GRIA4LMNATYRRIPK1NR1H4
SCHEMBL1653943 0.79 TRPA1 (0.48) TRPA1TYRRIPK1
SCHEMBL20748168 0.78 GRIA4 (0.47) GRIA4LMNATYRRIPK1TSHR
SCHEMBL8045399 0.78 LMNA (0.41) GRIA4LMNATYRNR1H4AKR1C3
SCHEMBL9366079 0.78 LMNA (0.41) GRIA4LMNATYRNR1H4AKR1C3
SCHEMBL1653050 0.78 TRPA1 (0.42) TRPA1RIPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2490993-A2 METHOD FOR PRODUCING M-SUBSTITUTED PHENYLALKANOLS BY MEANS OF ISOMERIZATION BASF SE (DE) 2012-08-29 EP disclosed
WO-2011048068-A2 METHOD FOR PRODUCING M-SUBSTITUTED PHENYLALKANOLS BY MEANS OF ISOMERIZATION BASF SE (DE) 2011-04-28 WO disclosed