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Sugi Predict / Compounds / Ammonia Solution, Strong

Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL16600069

Cc1c(C)c(C)c2c(C)cccc2c1N.N

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2A6 P11509 2/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CD44 P16070 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPT P10636 3/20 0.37
▸ KDM4E B2RXH2 2/20 0.37
▸ POLB P06746 2/20 0.37
▸ PSMD14 O00487 1/20 0.37
▸ MITF O75030 1/20 0.37
▸ LMNA P02545 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ APEX1 P27695 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ RAD52 P43351 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ESR2 Q92731 2/20 0.36
▸ CYP3A4 P08684 2/20 0.36
▸ TSHR P16473 1/20 0.36
▸ PIK3CA P42336 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16029928 0.89 CYP2A6 (0.44) CYP2A6CYP1A2CD44ALDH1A1MAPT
SCHEMBL8197963 0.81 CYP3A4 (0.48) CYP2A6CYP1A2CD44ALDH1A1MAPT
SCHEMBL23458352 0.81 CYP2A6 (0.44) CYP2A6CYP1A2CD44ALDH1A1MAPT
SCHEMBL2300447 0.80 CYP1A2 (0.52) CYP2A6CYP1A2ALDH1A1MAPTKDM4E
SCHEMBL31374647 0.80 CYP1A2 (0.52) CYP2A6CYP1A2ALDH1A1MAPTKDM4E
SCHEMBL10434554 0.79 CYP1A2 (0.58) CYP2A6CYP1A2ALDH1A1MAPTHPGD
SCHEMBL27955277 0.78 CYP2A6 (0.46) CYP2A6CYP1A2CD44ALDH1A1MAPT
SCHEMBL15352933 0.74 ALDH1A1 (0.46) CYP2A6CYP1A2CD44ALDH1A1MAPT
SCHEMBL9223063 0.74 POLB (0.44) CD44ALDH1A1MAPTKDM4EPOLB
Ammonia Solution, Strong SCHEMBL8197954 0.73 TSHR (0.40) CYP2A6CYP1A2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4045502-A1 PHOTOCHEMICAL PROCESS FOR PRODUCING (4R,4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1,6-NAPHTHYRIDIN-3-CARBOXAMIDE Bayer Aktiengesellschaft (DE) 2022-08-24 — — EP claimed
CN-114555598-A Photochemical process for the preparation of (4R,4S) -4- (4-cyano-2-methoxyphenyl) -5-ethoxy-2, 8-dimethyl-1, 4-dihydro-1, 6-naphthyridine-3-carboxamide 拜耳公司 2022-05-27 — — CN claimed
WO-2021074079-A1 PHOTOCHEMICAL PROCESS FOR PRODUCING (4R,4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1,6-NAPHTHYRIDIN-3-CARBOXAMIDE BAYER AKTIENGESELLSCHAFT (DE) 2021-04-22 — — WO claimed
CN-114555598-B Photochemical process for the preparation of (4R, 4S) -4- (4-cyano-2-methoxyphenyl) -5-ethoxy-2, 8-dimethyl-1, 4-dihydro-1, 6-naphthyridine-3-carboxamide 拜耳公司 2024-06-07 — — CN disclosed
EP-4045502-A1 PHOTOCHEMICAL PROCESS FOR PRODUCING (4R,4S)-4-(4-CYANO-2-METHOXYPHENYL)-5-ETHOXY-2,8-DIMETHYL-1,4-DIHYDRO-1,6-NAPHTHYRIDIN-3-CARBOXAMIDE Bayer Aktiengesellschaft (DE) 2022-08-24 — — EP disclosed
CN-114761393-A Heteroaryl substituted pyrazine derivatives as pesticides 拜耳动物保健有限责任公司 2022-07-15 — — CN disclosed
CN-114555598-A Photochemical process for the preparation of (4R,4S) -4- (4-cyano-2-methoxyphenyl) -5-ethoxy-2, 8-dimethyl-1, 4-dihydro-1, 6-naphthyridine-3-carboxamide 拜耳公司 2022-05-27 — — CN disclosed
CN-113243374-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2022-04-26 — — CN disclosed
CN-113939509-A Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2022-01-14 — — CN disclosed
CN-113243374-A Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-08-13 — — CN disclosed
CN-108477173-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-07-02 — — CN disclosed
EP-3092220-A1 VITAMIN C PRODRUGS AND USES THEREOF University of Florida Research Foundation, Inc. (US) 2016-11-16 — — EP disclosed
CN-106103414-A The substituted benzamides processed for arthropod 拜耳作物科学股份公司 2016-11-09 — — CN disclosed
US-20160264541-A1 VITAMIN C PRODRUGS AND USES THEREOF University of Florida Research Foundation, Inc.223 (US) 2016-09-15 — — US disclosed
CN-105873906-A Novel compounds for controlling arthropods 拜耳作物科学股份公司 2016-08-17 — — CN disclosed
CN-105392365-A Heterocyclic compounds known and new as pest control agents BAYER CROPSCIENCE AG 2016-03-09 — — CN disclosed
CN-105101800-A Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG 2015-11-25 — — CN disclosed
WO-2015048121-A1 VITAMIN C PRODRUGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-02 — — WO disclosed
CN-1254596-A Process for preparing composition to kill internal parasites BAYER AG (DE) 2000-05-31 — — CN disclosed
CN-1157623-A Supported ionic catalyst compositions EXXON CHEMICAL PATENTS INC (US) 1997-08-20 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264541-A1 VITAMIN C PRODRUGS AND USES THEREOF PROC, ADH7, PNPO CYP2A6 147/4885CYP1A2 154/4885CD44 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.