SCHEMBL16600148

SCHEMBL16600148

Cc1c(C)n(-c2cc(B3OC(C)(C)C(C)(C)O3)cc(-n3c(C)c(C)c4ccccc43)c2)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.40
LIPG Q9Y5X9 7/20 0.40
IRAK4 Q9NWZ3 1/20 0.34
KDM4E B2RXH2 2/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
JAK2 O60674 3/20 0.32
BTK Q06187 3/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 2/20 0.31
PRMT5 O14744 1/20 0.31
WDR77 Q9BQA1 1/20 0.31
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
P4HB P07237 1/20 0.31
IDO1 P14902 1/20 0.31
TDO2 P48775 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1154883 0.87 LPL (0.45) LPLLIPGIRAK4KDM4ECA1
SCHEMBL29445688 0.77 KDM4E (0.44) LPLLIPGIRAK4KDM4ECA1
SCHEMBL355715 0.77 KDM4E (0.44) LPLLIPGIRAK4KDM4ECA1
SCHEMBL3955039 0.77 LPL (0.39) LPLLIPGIRAK4KDM4ECA1
SCHEMBL30417090 0.77 LIPG (0.53) LPLLIPGIRAK4KDM4ECA1
SCHEMBL19697309 0.77 LIPG (0.53) LPLLIPGIRAK4KDM4ECA1
SCHEMBL11987879 0.75 LIPG (0.58) LPLLIPGKDM4ECA1CA2
SCHEMBL29662424 0.75 LPL (0.53) LPLLIPGIRAK4KDM4ECA1
SCHEMBL792421 0.75 LPL (0.53) LPLLIPGIRAK4KDM4ECA1
SCHEMBL29492600 0.75 LPL (0.53) LPLLIPGIRAK4KDM4ECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015046883-A1 COMPOUND FOR ORGANIC ELECTRICAL ELEMENT, ORGANIC ELECTRICAL ELEMENT USING SAME AND ELECTRONIC DEVICE THEREWITH 덕산네오룩스 주식회사 2015-04-02 WO disclosed