Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1659977 | 0.99 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9ABAZ2B | |
| SCHEMBL1660138 | 0.80 | BAZ2B (0.45) | MEN1KMT2ANPC1RAB9ABAZ2B | |
| SCHEMBL10635329 | 0.78 | SERPINE1 (0.50) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL7524221 | 0.75 | NPC1 (0.51) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL828645 | 0.75 | NPC1 (0.54) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL11595522 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL5695936 | 0.72 | CSNK2A1 (0.49) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL25262379 | 0.72 | TDP1 (0.56) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL10721944 | 0.72 | TDP1 (0.56) | MEN1KMT2ANPC1RAB9AMMP1 | |
| SCHEMBL4652939 | 0.71 | ALDH1A1 (0.55) | MEN1KMT2ANPC1RAB9AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306828-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxosmithkline LLC (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |