Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1660046 | 0.80 | MEN1 (0.43) | BAZ2BBAZ2AMEN1KMT2AJMJD6 | |
| SCHEMBL1659977 | 0.79 | MEN1 (0.44) | BAZ2BBAZ2AMEN1KMT2AJMJD6 | |
| SCHEMBL388580 | 0.78 | BAZ2B (0.70) | BAZ2BBAZ2AGAAMEN1KMT2A | |
| SCHEMBL1660685 | 0.74 | TSHR (0.53) | BAZ2BBAZ2AGAAMEN1KMT2A | |
| SCHEMBL4652766 | 0.74 | KMT2A (0.60) | EGFRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL9002096 | 0.73 | CHRNB4 (0.53) | EGFRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1642607 | 0.72 | ALDH1A1 (0.43) | MEN1KMT2A | |
| SCHEMBL23188226 | 0.70 | ATM (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4HTR4 | |
| SCHEMBL14944469 | 0.70 | CHRNB2 (0.50) | EGFRCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1660016 | 0.69 | TDP1 (0.47) | BAZ2BBAZ2AFLT3GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306828-A1 | PROLYL HYDROXYLASE INHIBITORS | Glaxosmithkline LLC (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |