Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.35 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600597 | 0.83 | PIK3CD (0.36) | SLC6A4ALDH1A1FFAR1FFAR4MAPT | |
| SCHEMBL28194119 | 0.78 | SLC6A4 (0.61) | SLC6A4CYP11B1CYP11B2MPOALDH1A1 | |
| SCHEMBL16600552 | 0.78 | MEN1 (0.46) | ALDH1A1MEN1KMT2ASLC5A2SLC5A1 | |
| SCHEMBL16600909 | 0.77 | ACACB (0.34) | SLC6A4SLC5A2 | |
| SCHEMBL7463754 | 0.76 | HTR2A (0.42) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21198742 | 0.74 | KEAP1 (0.52) | MEN1MAPTKMT2ASLC5A2SLC5A1 | |
| SCHEMBL16600894 | 0.73 | SLC5A2 (0.44) | ALDH1A1MEN1KMT2ASLC5A2SLC5A1 | |
| SCHEMBL2092054 | 0.73 | SLC6A4 (0.56) | SLC6A4CYP11B1CYP11B2MPOALDH1A1 | |
| SCHEMBL2096216 | 0.72 | SLC6A4 (0.49) | SLC6A4CYP11B1CYP11B2MPOALDH1A1 | |
| SCHEMBL2575166 | 0.72 | SLC6A4 (0.61) | SLC6A4CYP11B1CYP11B2MPOTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895490-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-07-22 | — | — | EP | disclosed |
| WO-2015043511-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |