Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 11/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16600894 | 0.83 | SLC5A2 (0.44) | MEN1KMT2ASLC5A2SMN1; SMN2KDM4E | |
| SCHEMBL16600597 | 0.81 | PIK3CD (0.36) | SLC5A2ALDH1A1 | |
| SCHEMBL16600909 | 0.81 | ACACB (0.34) | SLC5A2LMNA | |
| SCHEMBL16600928 | 0.78 | SLC5A2 (0.41) | SLC5A2SLC5A1 | |
| SCHEMBL16600577 | 0.78 | SLC6A4 (0.52) | MEN1KMT2ASLC5A2SLC5A1ALDH1A1 | |
| SCHEMBL3622807 | 0.78 | MEN1 (0.66) | MEN1KMT2ASLC5A2SMN1; SMN2KDM4E | |
| SCHEMBL7463754 | 0.77 | HTR2A (0.42) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL21198742 | 0.76 | KEAP1 (0.52) | MEN1KMT2ASLC5A2HPGDSLC5A1 | |
| SCHEMBL7785326 | 0.73 | NQO1 (0.47) | MEN1KMT2ASMN1; SMN2KDM4EHPGD | |
| SCHEMBL16600692 | 0.73 | SLC5A2 (0.47) | MEN1KMT2ASLC5A2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112014494-A | Method for separating eggliflozin and isomer thereof | 上海柏狮生物科技有限公司 | 2020-12-01 | — | — | CN | disclosed |
| EP-2895490-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-07-22 | — | — | EP | disclosed |
| WO-2015043511-A1 | GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-04-02 | — | — | WO | disclosed |