SCHEMBL16600692

SCHEMBL16600692

CCOc1ccc(Cc2c[c]ccc2Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 13/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
SLC5A1 P13866 8/20 0.44
DHFR P00374 1/20 0.43
NQO1 P15559 1/20 0.42
ADRA2A P08913 1/20 0.42
SLC5A11 Q8WWX8 1/20 0.42
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27788342 0.98 SLC5A2 (0.46) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL27788263 0.94 SLC5A2 (0.44) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
Magnesium Chloride Anhydrous SCHEMBL29084875 0.94 SLC5A2 (0.44) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
Chlorolithium SCHEMBL29084967 0.92 SLC5A2 (0.42) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
Chlorolithium SCHEMBL29084912 0.92 SLC5A2 (0.42) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL29041345 0.84 SLC5A2 (0.35) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL16601002 0.78 SLC5A2 (0.45) SLC5A2SMN1; SMN2KDM4ESLC5A1LMNA
SCHEMBL3622807 0.78 MEN1 (0.66) SLC5A2MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL27820545 0.77 SLC5A2 (0.35) SLC5A2SLC5A1
SCHEMBL7785329 0.77 NQO1 (0.56) SMN1; SMN2KDM4EHPGDDHFRNQO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328100-B2 Process for the preparation of β-C-arylglucosides SCINOPHARM TAIWAN, LTD. (TW) 2016-05-03 US claimed
WO-2015155739-A1 PROCESS FOR THE PREPARATION OF BETA-C-ARYLGLUCOSIDES SCINOPHARM TAIWAN, LTD. (TW) 2015-10-15 WO claimed
US-20150291569-A1 PROCESS FOR THE PREPARATION OF beta-C-ARYLGLUCOSIDES SCINOPHARM TAIWAN, LTD. (TW) 2015-10-15 US claimed
CN-108675976-B 6-halogenated glucose carbon glycoside and preparation method and application thereof 浙江宏元药业股份有限公司 2020-07-14 CN disclosed
CN-104619713-B Oxabicyclo derivative, preparation method and applications 四川海思科制药有限公司 2017-06-16 CN disclosed
US-9328100-B2 Process for the preparation of β-C-arylglucosides SCINOPHARM TAIWAN, LTD. (TW) 2016-05-03 US disclosed
CN-103450214-B Glucopyranosyl derivatives, its preparation method and in application pharmaceutically SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-06 CN disclosed
CN-103450214-B Glucopyranosyl derivatives, its preparation method and in application pharmaceutically SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-06 CN disclosed
US-20150291569-A1 PROCESS FOR THE PREPARATION OF beta-C-ARYLGLUCOSIDES SCINOPHARM TAIWAN, LTD. (TW) 2015-10-15 US disclosed
EP-2895490-A1 GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE Sunshine Lake Pharma Co., Ltd. (CN) 2015-07-22 EP disclosed
WO-2015043511-A1 GLUCOPYRANOSYL DERIVATIVES AND THEIR USES IN MEDICINE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2015-04-02 WO disclosed
CN-102112483-A Solid forms of (2S,3R,4R,5S,6R) -2- (4-chloro-3- (4-ethoxybenzyl) phenyl) -6- (methylthio) tetrahydro-2H-pyran-3, 4, 5-triol and methods of use thereof LEXICON PHARMACEUTICALS INC 2011-06-29 CN disclosed
CN-101801989-A Methods and compounds for the preparation of sodium-glucose cotransporter 2 inhibitors LEXICON PHARMACEUTICALS INC 2010-08-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291569-A1 PROCESS FOR THE PREPARATION OF beta-C-ARYLGLUCOSIDES GANC, UGCG, UGGT1 SLC5A2 68/4885MEN1 3880/4885KMT2A 4071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.