Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5463742 | 0.82 | CYP2C9 (0.44) | LMNACYP2D6CYP2C9CES2CES1 | |
| SCHEMBL5559079 | 0.82 | CYP1A2 (0.55) | MAPTCYP1A2CYP2C19CES2CES1 | |
| SCHEMBL622334 | 0.80 | BRD4 (0.59) | CYP3A4LMNACYP1A2ADORA3CYP2D6 | |
| SCHEMBL330957 | 0.80 | HDAC3 (0.44) | LMNATDP1CES2CES1ALDH1A1 | |
| SCHEMBL23727587 | 0.79 | CES2 (0.67) | CYP3A4LMNACYP2D6TDP1CES2 | |
| SCHEMBL2573939 | 0.79 | CES2 (0.67) | CYP3A4LMNACYP2D6TDP1CES2 | |
| SCHEMBL8880335 | 0.79 | SRC (0.55) | ESR1ESR2MAPTCYP3A4LMNA | |
| SCHEMBL10970686 | 0.77 | ESR1 (0.43) | ESR1ESR2MAPTCYP3A4LMNA | |
| SCHEMBL10970682 | 0.77 | ESR1 (0.43) | ESR1ESR2MAPTCYP3A4LMNA | |
| SCHEMBL8933321 | 0.77 | ALDH1A1 (0.47) | MAPTLMNACYP1A2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102943-A | Flame-retardant anti-aging phenolic resin coating and preparation method thereof | 无锡市造漆厂有限公司 | 2023-05-12 | — | — | CN | claimed |
| CN-116102943-A | Flame-retardant anti-aging phenolic resin coating and preparation method thereof | 无锡市造漆厂有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-109810073-B | 4-arylthiazole derivatives and pharmaceutical compositions thereof | 南京海辰药业股份有限公司 | 2023-01-06 | — | — | CN | disclosed |
| EP-3036221-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C]PYRROLE NEGATIVE MODULATORS OF NR2B | Luc Therapeutics, Inc. (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015048507-A1 | SELECTIVE OCTAHYDRO-CYCLOPENTA[C] PYRROLE NEGATIVE MODULATORS OF NR2B | MNEMOSYNE PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |