SCHEMBL16601669

SCHEMBL16601669

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccc(C(C)O)cc1)C3=O

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.44
ANPEP P15144 4/20 0.44
ALDH1A1 P00352 3/20 0.41
POLB P06746 2/20 0.41
KDM4E B2RXH2 2/20 0.41
CYP1A2 P05177 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
APAF1 O14727 1/20 0.40
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
TYMS P04818 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
USP2 O75604 1/20 0.35
ATM Q13315 1/20 0.35
KEAP1 Q14145 1/20 0.35
NFE2L2 Q16236 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601652 0.89 DPP4 (0.45) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL16601668 0.85 POLB (0.59) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL13045764 0.83 DPP4 (0.55) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL16602003 0.83 ALDH1A1 (0.48) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL16601641 0.81 ALDH1A1 (0.46) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL16602041 0.79 DPP4 (0.48) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL12656452 0.79 DPP4 (0.50) DPP4ANPEPALDH1A1POLBKDM4E
SCHEMBL16602024 0.78 DPP4 (0.50) DPP4ANPEPALDH1A1KDM4ENPC1
SCHEMBL17263572 0.77 MEN1 (0.52) DPP4ANPEPALDH1A1CYP1A2CYP2C19
SCHEMBL16601644 0.77 DPP4 (0.47) DPP4ANPEPALDH1A1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed