SCHEMBL16601668

SCHEMBL16601668

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccc(O)cc1)C3=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.59
APAF1 O14727 1/20 0.59
ANPEP P15144 4/20 0.58
DPP4 P27487 4/20 0.58
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
ESR1 P03372 3/20 0.46
ESR2 Q92731 2/20 0.46
NR1H3 Q13133 1/20 0.45
MEN1 O00255 2/20 0.44
USP2 O75604 2/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 1/20 0.44
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 3/20 0.44
CYP1A2 P05177 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
BRD4 O60885 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13045764 0.88 DPP4 (0.55) POLBANPEPDPP4NPC1RAB9A
SCHEMBL16602003 0.88 ALDH1A1 (0.48) POLBAPAF1ANPEPDPP4NPC1
SCHEMBL16601641 0.85 ALDH1A1 (0.46) POLBAPAF1ANPEPDPP4NR1H3
SCHEMBL16601669 0.85 DPP4 (0.44) POLBAPAF1ANPEPDPP4NPC1
SCHEMBL12656452 0.82 DPP4 (0.50) POLBANPEPDPP4MEN1USP2
SCHEMBL16602024 0.82 DPP4 (0.50) ANPEPDPP4NPC1RAB9AMEN1
SCHEMBL17263572 0.81 MEN1 (0.52) ANPEPDPP4NR1H3MEN1USP2
SCHEMBL16601670 0.81 DPP4 (0.53) ANPEPDPP4ESR1ESR2NR1H3
SCHEMBL16602041 0.80 DPP4 (0.48) POLBANPEPDPP4MEN1USP2
SCHEMBL16601652 0.79 DPP4 (0.45) POLBANPEPDPP4NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed