SCHEMBL16601670

SCHEMBL16601670

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1O)C3=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 5/20 0.53
ANPEP P15144 4/20 0.53
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
TLR9 Q9NR96 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
CRHBP P24387 1/20 0.42
CASP1 P29466 1/20 0.42
BRCA1 P38398 1/20 0.42
CASP7 P55210 1/20 0.42
HBB P68871 1/20 0.42
CRHR2 Q13324 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TYMS P04818 1/20 0.41
NR1H3 Q13133 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17263572 0.91 MEN1 (0.52) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL13045764 0.87 DPP4 (0.55) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL12656452 0.81 DPP4 (0.50) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL16601668 0.81 POLB (0.59) DPP4ANPEPMEN1KMT2AUSP2
SCHEMBL16602024 0.81 DPP4 (0.50) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL29381488 0.79 DPP4 (0.56) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL12556946 0.79 ANPEP (0.55) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL16602041 0.79 DPP4 (0.48) DPP4ANPEPMEN1KMT2AMAPT
SCHEMBL16601643 0.79 MEN1 (0.60) MEN1KMT2AMAPTHTTTLR9
SCHEMBL22221562 0.78 ANPEP (0.66) DPP4ANPEPMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4122930-A1 PHOTOELECRIC CONVERSION ELEMENT AND PHOTOELECRIC CONVERSION DEVICE COMPRISING SAID PHOTOELECRIC CONVERSION ELEMENT Canon Kabushiki Kaisha (JP) 2023-01-25 EP disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed