Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DNM2 | P50570 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18470133 | 0.90 | MEN1 (0.52) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL2150841 | 0.88 | MEN1 (0.55) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL8079827 | 0.82 | ESR1 (0.72) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL29009411 | 0.81 | KMT2A (0.64) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL29009437 | 0.81 | L3MBTL1 (0.64) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL16601654 | 0.80 | KMT2A (0.44) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL9588431 | 0.79 | ANPEP (0.58) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL16601670 | 0.79 | DPP4 (0.53) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL16864816 | 0.78 | MEN1 (0.48) | MEN1KMT2AMAPTHTTTLR9 | |
| SCHEMBL17946433 | 0.78 | APEX1 (0.69) | MEN1KMT2AMAPTHTTTLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10596164-B2 | Anti-clostridium compounds | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2020-03-24 | — | — | US | disclosed |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETEN SCHAPPELIJK ONDERZOEK TNO (NL) | 2017-02-09 | — | — | US | disclosed |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETEN SCHAPPELIJK ONDERZOEK TNO (NL) | 2017-02-09 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596164-B2 | Anti-clostridium compounds | CLPP, ATP5F1A, ATP5F1C | MEN1 4601/4885KMT2A 4512/4885MAPT 3960/4885 |
| US-20170035750-A1 | NEW ANTI-CLOSTRIDIUM COMPOUNDS | ANTXR2, CLPP, DAD1 | MEN1 4740/4885KMT2A 4578/4885MAPT 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.