SCHEMBL16601693

SCHEMBL16601693

CCc1cccc(C)c1N1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(CCCN(CCO)CCO)C3=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 2/20 0.45
MEN1 O00255 3/20 0.44
ALDH1A1 P00352 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 2/20 0.44
LMNA P02545 2/20 0.44
PABPC1 P11940 2/20 0.44
RGS12 O14924 1/20 0.44
HTT P42858 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
BCHE P06276 3/20 0.44
ACHE P22303 3/20 0.44
APP P05067 1/20 0.44
STAT3 P40763 1/20 0.42
HIF1A Q16665 1/20 0.42
ANPEP P15144 3/20 0.41
DPP4 P27487 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601663 0.87 KDM4E (0.58) TERTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL16601812 0.83 HTT (0.53) TERTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL16601816 0.82 MEN1 (0.46) TERTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL16602024 0.81 DPP4 (0.50) MEN1ALDH1A1KMT2AKDM4ENPC1
SCHEMBL13045764 0.80 DPP4 (0.55) MEN1ALDH1A1KMT2AKDM4ENPC1
SCHEMBL12656452 0.78 DPP4 (0.50) MEN1ALDH1A1KMT2AKDM4ELMNA
SCHEMBL12556882 0.77 DPP4 (0.42) TERTMEN1ALDH1A1KMT2ANPC1
SCHEMBL31674304 0.75 STAT3 (0.67) TERTMEN1ALDH1A1KMT2AKDM4E
SCHEMBL10719190 0.74 HEXA (0.68) MEN1ALDH1A1KMT2AKDM4ELMNA
SCHEMBL17263572 0.74 MEN1 (0.52) MEN1ALDH1A1KMT2AANPEPDPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed