SCHEMBL16601812

SCHEMBL16601812

CCc1cccc(C)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CCCCCO)C5=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.53
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.53
RGS12 O14924 2/20 0.53
KMT2A Q03164 2/20 0.53
NPC1 O15118 1/20 0.53
LMNA P02545 1/20 0.53
PABPC1 P11940 1/20 0.53
RECQL P46063 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
STAT3 P40763 1/20 0.44
HIF1A Q16665 1/20 0.44
TERT O14746 3/20 0.44
ANPEP P15144 3/20 0.41
DPP4 P27487 3/20 0.41
BRD1 O95696 2/20 0.41
TAF1 P21675 2/20 0.41
BRPF1 P55201 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601663 0.96 KDM4E (0.58) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL16601816 0.87 MEN1 (0.46) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL16601693 0.83 TERT (0.45) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL16601631 0.83 DPP4 (0.46) KDM4EALDH1A1MEN1KMT2ALMNA
SCHEMBL16602024 0.81 DPP4 (0.50) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL14302831 0.80 KDM4E (0.83) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL13045764 0.80 DPP4 (0.55) HTTKDM4EALDH1A1MEN1KMT2A
SCHEMBL16601825 0.79 DPP4 (0.43) ALDH1A1MEN1KMT2ATERTANPEP
SCHEMBL14309279 0.79 KDM4E (0.86) HTTKDM4EALDH1A1MEN1RGS12
SCHEMBL15764234 0.78 DPP4 (0.38) HTTKDM4EALDH1A1MEN1RGS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed