Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14927359 | 0.88 | KMO (0.58) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL16601702 | 0.87 | KMO (0.42) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL16602023 | 0.85 | KMO (0.61) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL16601734 | 0.84 | MAP4K4 (0.46) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL12163407 | 0.81 | PTPRC (0.46) | RXRARXRBERN1LMNAPTPRC | |
| SCHEMBL15764214 | 0.81 | PTPRC (0.70) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL6054726 | 0.79 | AKR1C3 (0.61) | KMONPC1RAB9AKMT2AMRGPRX4 | |
| SCHEMBL16601809 | 0.77 | KMO (0.38) | RXRARXRBERN1LMNAGAA | |
| SCHEMBL17718223 | 0.76 | TTR (0.56) | GAAPTPRCMEN1MAPTTHRB | |
| SCHEMBL12163410 | 0.76 | TTR (0.47) | RXRARXRBERN1PTPRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |