Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | AXL | P30530 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.40 |
| ▸ | DDT | P30046 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16602016 | 0.87 | MAP4K4 (0.56) | MAP4K4AXLKMORXRARXRB | |
| SCHEMBL16601714 | 0.84 | RXRA (0.46) | MRGPRX4NR4A2KMORXRARXRB | |
| SCHEMBL14927359 | 0.83 | KMO (0.58) | MRGPRX4NR4A2KMORXRARXRB | |
| SCHEMBL16601702 | 0.80 | KMO (0.42) | MRGPRX4KMORXRARXRBDDT | |
| SCHEMBL6054726 | 0.74 | AKR1C3 (0.61) | MRGPRX4NR4A2KMO | |
| SCHEMBL17174087 | 0.72 | KMO (0.42) | MRGPRX4KMOLMNAGAAERN1 | |
| SCHEMBL17174082 | 0.71 | KMO (0.44) | MRGPRX4KMORXRARXRBLMNA | |
| SCHEMBL16601809 | 0.70 | KMO (0.38) | MRGPRX4NR4A2KMORXRARXRB | |
| SCHEMBL1679150 | 0.70 | CHEK2 (0.71) | MAP4K4CHEK2NEK1 | |
| SCHEMBL12556925 | 0.69 | NPC1 (0.50) | MAP4K4AXLLMNACHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |