Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.87 |
| ▸ | RAB9A | P51151 | 2/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | ESR1 | P03372 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.60 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.60 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.60 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16521526 | 0.93 | NPC1 (1.00) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL18201564 | 0.89 | NPC1 (0.69) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL16601770 | 0.87 | NPC1 (0.66) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL18198714 | 0.87 | NPC1 (0.66) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL17278253 | 0.85 | NPC1 (0.62) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL18470134 | 0.84 | NPC1 (0.82) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL9588495 | 0.81 | ESR1 (1.00) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL1662738 | 0.81 | ESR1 (0.80) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL28563147 | 0.81 | NPC1 (0.70) | NPC1RAB9AKDM4EPOLBESR1 | |
| SCHEMBL3628513 | 0.81 | KMT2A (0.71) | NPC1RAB9AKDM4EPOLBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |