Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | USP2 | O75604 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.64 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.64 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159196 | 0.86 | POLB (0.63) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL1518037 | 0.84 | ALDH1A1 (0.68) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL16521526 | 0.83 | NPC1 (1.00) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL5168401 | 0.83 | KMT2A (0.73) | KMT2AMEN1USP2L3MBTL1ALDH1A1 | |
| SCHEMBL29042579 | 0.82 | NPC1 (0.68) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL30495925 | 0.82 | NPC1 (0.68) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL16601773 | 0.81 | NPC1 (0.87) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL5162903 | 0.81 | KMT2A (0.57) | NPC1RAB9AKMT2AMEN1USP2 | |
| SCHEMBL25742121 | 0.80 | ALDH1A1 (0.58) | KMT2AMEN1USP2L3MBTL1ALDH1A1 | |
| SCHEMBL1662738 | 0.78 | ESR1 (0.80) | NPC1RAB9AKMT2AMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112645877-B | Fluorescent stress response material based on naphthalimide derivative and preparation and application thereof | 上海工程技术大学 | 2022-08-26 | — | — | CN | claimed |
| CN-112645877-A | Fluorescent stress response material based on naphthalimide derivative and preparation and application thereof | 上海工程技术大学 | 2021-04-13 | — | — | CN | claimed |
| CN-112645877-B | Fluorescent stress response material based on naphthalimide derivative and preparation and application thereof | 上海工程技术大学 | 2022-08-26 | — | — | CN | disclosed |
| CN-112645877-A | Fluorescent stress response material based on naphthalimide derivative and preparation and application thereof | 上海工程技术大学 | 2021-04-13 | — | — | CN | disclosed |