Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 2/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15764225 | 0.84 | BACE1 (0.68) | BACE1PTPN1MEN1KMT2AMAOA | |
| SCHEMBL16601787 | 0.75 | BACE1 (0.69) | BACE1AURKADYRK1APTPN1CYP1A2 | |
| SCHEMBL14305571 | 0.73 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1MEN1 | |
| SCHEMBL28865245 | 0.71 | BACE1 (0.66) | BACE1PTPN1MEN1KMT2AMAOA | |
| SCHEMBL24389333 | 0.71 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1MEN1 | |
| SCHEMBL16601761 | 0.71 | BACE1 (0.69) | BACE1AURKADYRK1APTPN1PTPRC | |
| SCHEMBL29647640 | 0.71 | BACE1 (0.78) | BACE1AURKADYRK1APTPN1MEN1 | |
| SCHEMBL16601788 | 0.71 | BACE1 (0.60) | BACE1PTPN1MEN1KMT2AMAOA | |
| SCHEMBL27006529 | 0.71 | BACE1 (0.78) | BACE1AURKADYRK1APTPN1MEN1 | |
| SCHEMBL16601766 | 0.68 | PTPRC (0.45) | BACE1PTPRCALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |