Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.69 |
| ▸ | AURKA | O14965 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14305571 | 0.82 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL24849449 | 0.77 | BACE1 (0.68) | BACE1AURKADYRK1APTPN1HSD17B1 | |
| SCHEMBL16601761 | 0.77 | BACE1 (0.69) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL312389 | 0.75 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL31423340 | 0.75 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL16601786 | 0.75 | BACE1 (0.57) | BACE1AURKADYRK1APTPN1CYP3A4 | |
| SCHEMBL24389333 | 0.74 | BACE1 (1.00) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL22220312 | 0.73 | BACE1 (0.68) | BACE1AURKADYRK1APTPN1P4HB | |
| SCHEMBL15764239 | 0.72 | HSD17B1 (0.48) | HSD17B1HSD17B2TDP2CYP3A4CYP2C9 | |
| SCHEMBL22182158 | 0.72 | TDP2 (0.51) | HSD17B1HSD17B2TDP2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-9012112-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-04-21 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |