Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.57 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PTPRC | P08575 | 4/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CDC25A | P30304 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121287 | 0.77 | BACE1 (0.53) | BACE1GAPDHPTPN1PTPRCCDC25B | |
| SCHEMBL24849449 | 0.74 | BACE1 (0.68) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL16601796 | 0.74 | BACE1 (0.66) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL5485068 | 0.74 | BACE1 (1.00) | BACE1GAPDHPTPN1PTPRCCDC25B | |
| SCHEMBL29673492 | 0.74 | BACE1 (1.00) | BACE1GAPDHPTPN1PTPRCCDC25B | |
| SCHEMBL3189065 | 0.72 | DRD1 (0.45) | MAOA | |
| SCHEMBL16601788 | 0.71 | BACE1 (0.60) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL16601979 | 0.71 | BACE1 (0.65) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL28246092 | 0.71 | BACE1 (0.60) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL29021327 | 0.70 | BRD4 (0.38) | MEN1ALDH1A1GAAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |