Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.65 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.57 |
| ▸ | KMO | O15229 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.49 |
| ▸ | PTPRC | P08575 | 3/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673492 | 0.80 | BACE1 (1.00) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| SCHEMBL5485068 | 0.80 | BACE1 (1.00) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| SCHEMBL24849449 | 0.80 | BACE1 (0.68) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| SCHEMBL27734065 | 0.78 | BACE1 (0.69) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| SCHEMBL16601796 | 0.76 | BACE1 (0.66) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| SCHEMBL30259065 | 0.76 | KMO (0.73) | KMONR1H4 | |
| SCHEMBL2213546 | 0.76 | KMO (0.73) | KMONR1H4 | |
| SCHEMBL16602021 | 0.76 | KMO (0.49) | BACE1KMOTTR | |
| SCHEMBL16601788 | 0.76 | BACE1 (0.60) | BACE1CDC25BPTPN1PTPRCPTPRF | |
| Methylamine SCHEMBL3277347 | 0.75 | BACE1 (0.89) | BACE1CDC25BPTPN1PTPRCPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2680079-B1 | Electrophotographic photosensitive member, process catridge, and electrophotographic apparatus | CANON KK (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |