Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 1.00 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.70 |
| ▸ | PTPRC | P08575 | 3/20 | 0.70 |
| ▸ | CDC25B | P30305 | 3/20 | 0.70 |
| ▸ | PTPRF | P10586 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | CDC25A | P30304 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29673492 | 1.00 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| Methylamine SCHEMBL3277347 | 0.94 | BACE1 (0.89) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL5139479 | 0.86 | PTPN1 (0.76) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL30433091 | 0.86 | PTPN1 (0.76) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL6555840 | 0.86 | BACE1 (0.75) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL25834756 | 0.86 | BACE1 (0.75) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL11048150 | 0.84 | BACE1 (0.72) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL13020950 | 0.84 | BACE1 (0.72) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL312389 | 0.84 | BACE1 (1.00) | BACE1PTPN1PTPRCCDC25BPTPRF | |
| SCHEMBL28556962 | 0.84 | BACE1 (0.72) | BACE1PTPN1PTPRCCDC25BPTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118176293-A | SIRPalpha-deficient macrophages for the treatment of cancer | 佐治亚州立大学研究基金会公司 | 2024-06-11 | — | — | CN | claimed |
| US-20230220342-A1 | SIRPa Deficient Macrophages for Treating Cancer | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-07-13 | — | — | US | claimed |
| WO-2023076813-A1 | SIRPα DEFICIENT MACROPHAGES FOR TREATING CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-05-04 | — | — | WO | claimed |
| CN-115803092-A | SIRP alpha deficient macrophages for the treatment of cancer | 乔治亚州立大学研究基金公司 | 2023-03-14 | — | — | CN | claimed |
| EP-4139003-A1 | SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER | Georgia State University Research Foundation, Inc. (US) | 2023-03-01 | — | — | EP | claimed |
| CN-114805398-A | Preparation method of ecteinascidin compound | 江苏恒瑞医药股份有限公司 | 2022-07-29 | — | — | CN | claimed |
| WO-2021217038-A1 | SIRPα DEFICIENT MACROPHAGES FOR TREATING CANCER | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-28 | — | — | WO | claimed |
| US-4460674-A | GALLIC ACID DERIVATIVES AND NAPOHTHOQUINONES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | claimed |
| US-6444385-B1 | — | — | None | — | — | US | disclosed |
| US-20260149060-A1 | Devices, Systems, and Methods for Rejuvenating Energy Devices | Sonocharge Energy, Inc (US) | 2026-05-28 | — | — | US | disclosed |
| US-20250333698-A1 | SIRPa DEFICIENT MACROPHAGES FOR TREATING CANCER | UNIV GEORGIA STATE RES FOUND (US) | 2025-10-30 | — | — | US | disclosed |
| CN-119528710-A | 2, 3-Disubstituted naphthoquinone compound, application and preparation method thereof | 中国农业科学院兰州畜牧与兽药研究所 | 2025-02-28 | — | — | CN | disclosed |
| EP-4423251-A1 | SIRP ALPHA DEFICIENT MACROPHAGES FOR TREATING CANCER | Georgia State University Research Foundation, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118176293-A | SIRPalpha-deficient macrophages for the treatment of cancer | 佐治亚州立大学研究基金会公司 | 2024-06-11 | — | — | CN | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| US-4752547-A | RECORDING LAYER CONTAINS REDUCING AGENT, LEWIS BASE COMPLEX, AND REDUCIBLE DYE FORMING COMPOUND | EASTMAN KODAK COMPANY (US) | 1988-06-21 | — | — | US | disclosed |
| US-4727008-A | MULTILAYER-IMAGEWISE EXPOSURE TO ELECTRICAL CHARGES OF DIFFERENT POLARITIES TO GIVE DEVELOPABLE IMAGES | EASTMAN KODAK COMPANY (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4460674-A | GALLIC ACID DERIVATIVES AND NAPOHTHOQUINONES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260149060-A1 | Devices, Systems, and Methods for Rejuvenating Energy Devices | TERT, WRN, SIRT3 | BACE1 3146/4885PTPN1 3641/4885PTPRC 2788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.