SCHEMBL16601804

SCHEMBL16601804

CCc1cccc(CC)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CC(=O)O)C5=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.51
ALDH1A1 P00352 2/20 0.51
MEN1 O00255 1/20 0.51
CYP1A2 P05177 1/20 0.51
MAPT P10636 1/20 0.51
AKR1B1 P15121 1/20 0.51
HPGD P15428 1/20 0.51
ALOX15 P16050 1/20 0.51
KMT2A Q03164 1/20 0.51
HSD17B10 Q99714 1/20 0.51
ANPEP P15144 2/20 0.50
DPP4 P27487 2/20 0.50
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
PIN1 Q13526 1/20 0.44
PIN4 Q9Y237 1/20 0.44
TERT O14746 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8070665 0.87 ANPEP (0.59) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL11947524 0.83 ANPEP (0.50) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL13148744 0.82 KDM4E (0.62) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL16601630 0.81 ANPEP (0.54) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL16601771 0.81 PTGER4 (0.49) KDM4EALDH1A1MEN1CYP1A2HPGD
SCHEMBL22221562 0.81 ANPEP (0.66) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL16601822 0.80 ANPEP (0.50) KDM4EALDH1A1HPGDKMT2AHSD17B10
SCHEMBL24976892 0.79 ANPEP (0.51) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL16601982 0.79 CA12 (0.49) KDM4EALDH1A1MEN1CYP1A2MAPT
SCHEMBL16601811 0.78 ANPEP (0.50) KDM4EALDH1A1MEN1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed