Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 3/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601837 | 0.84 | CA12 (0.43) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL13148744 | 0.81 | KDM4E (0.62) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL16601804 | 0.79 | KDM4E (0.51) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL6690679 | 0.78 | NR1H3 (0.61) | CA12CA9ALDH1A1AKR1B1NR1H2 | |
| SCHEMBL12606551 | 0.76 | KDM4E (0.56) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL16601772 | 0.75 | NR1H3 (0.50) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL860250 | 0.75 | CA12 (0.70) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL15521020 | 0.73 | CA12 (0.49) | CA12CA9KMT2AKDM4EMEN1 | |
| SCHEMBL16601836 | 0.73 | ALDH1A1 (0.54) | KMT2AKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22018376 | 0.72 | MEN1 (0.55) | CA12CA9KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993205-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2015-03-31 | — | — | US | disclosed |