SCHEMBL16601811

SCHEMBL16601811

CCc1cccc(CC)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(c1ccccc1CO)C5=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.50
DPP4 P27487 2/20 0.50
ALDH1A1 P00352 4/20 0.43
MAPT P10636 4/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 6/20 0.42
MEN1 O00255 5/20 0.42
USP2 O75604 2/20 0.42
GAA P10253 2/20 0.42
CRHBP P24387 2/20 0.42
CRHR2 Q13324 2/20 0.42
CASP1 P29466 1/20 0.42
BRCA1 P38398 1/20 0.42
CASP7 P55210 1/20 0.42
HBB P68871 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12556946 0.95 ANPEP (0.55) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL16601810 0.90 ANPEP (0.48) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL8070665 0.87 ANPEP (0.59) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL16601708 0.85 ANPEP (0.52) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL16417481 0.84 NR1H2 (0.50) ALDH1A1MAPTKMT2AMEN1USP2
SCHEMBL16601630 0.81 ANPEP (0.54) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL22221562 0.81 ANPEP (0.66) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL17263572 0.80 MEN1 (0.52) ANPEPDPP4ALDH1A1MAPTCYP1A2
SCHEMBL16601826 0.80 POLB (0.43) ALDH1A1MAPTCYP1A2CYP2C19TDP1
SCHEMBL16601832 0.80 ANPEP (0.50) ANPEPDPP4ALDH1A1MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed