SCHEMBL16601832

SCHEMBL16601832

CCc1cccc(CC)c1N1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(c1cccc(CO)c1)C5=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.50
DPP4 P27487 2/20 0.50
NPC1 O15118 2/20 0.46
RAB9A P51151 1/20 0.46
NR1H3 Q13133 2/20 0.41
KDM4E B2RXH2 5/20 0.40
POLB P06746 3/20 0.40
MGLL Q99685 1/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
ALDH1A1 P00352 4/20 0.40
USP2 O75604 3/20 0.40
KEAP1 Q14145 3/20 0.40
NFE2L2 Q16236 3/20 0.40
HPGD P15428 2/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
CASP1 P29466 1/20 0.40
HTT P42858 1/20 0.40
CASP7 P55210 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601770 0.86 NPC1 (0.66) ANPEPDPP4NPC1RAB9ANR1H3
SCHEMBL8070665 0.83 ANPEP (0.59) ANPEPDPP4NPC1RAB9AKDM4E
SCHEMBL16601803 0.83 KMT2A (0.56) ANPEPDPP4NPC1RAB9AKDM4E
SCHEMBL16601811 0.80 ANPEP (0.50) ANPEPDPP4NR1H3KDM4EPOLB
SCHEMBL16601630 0.79 ANPEP (0.54) ANPEPDPP4KDM4EPOLBMEN1
SCHEMBL16601771 0.78 PTGER4 (0.49) ANPEPDPP4KDM4EPOLBMEN1
SCHEMBL16601821 0.78 ANPEP (0.48) ANPEPDPP4NPC1RAB9AKDM4E
SCHEMBL13084664 0.78 MGLL (0.63) NPC1RAB9ANR1H3KDM4EPOLB
SCHEMBL22221562 0.78 ANPEP (0.66) ANPEPDPP4NPC1RAB9AKDM4E
SCHEMBL16601675 0.78 KMT2A (0.58) ANPEPDPP4NPC1RAB9ANR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed
US-8993205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-03-31 US disclosed