Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601545 | 0.94 | CYP19A1 (0.44) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL16601873 | 0.92 | CYP19A1 (0.46) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL16602199 | 0.90 | CYP19A1 (0.47) | CYP19A1MAPTPOLBPKMCISD1 | |
| SCHEMBL17510056 | 0.88 | CYP19A1 (0.40) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL16601541 | 0.85 | CYP19A1 (0.51) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL10732244 | 0.81 | POLB (0.51) | MAPTPOLBSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL16602198 | 0.81 | CYP19A1 (0.56) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL4706929 | 0.76 | CYP19A1 (0.54) | CYP19A1MAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL10989465 | 0.73 | NSD2 (0.52) | MAPTPOLBCISD1SMN1; SMN2RAB9A | |
| SCHEMBL9619539 | 0.72 | CYP19A1 (0.47) | CYP19A1MAPTPOLBPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993260-B2 | Fluorescence-based viability staining method using a membrane permeable flourescent dye and membrane impermeable fluorescence quencher | CHARLES RIVER LABORATORIES, INC. (US) | 2015-03-31 | — | — | US | disclosed |