SCHEMBL16601545

SCHEMBL16601545

C[N+](C)(C)CCCNc1ccc(Cl)c2c1C(=O)c1c(NCCC[N+](C)(C)C)ccc(NCCC[N+](C)(C)C)c1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.44
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
BLM P54132 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
LMNA P02545 3/20 0.36
NSD2 O96028 3/20 0.36
PKM P14618 3/20 0.36
USP2 O75604 2/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 2/20 0.36
RECQL P46063 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 2/20 0.36
MTOR P42345 2/20 0.36
RAB9A P51151 2/20 0.36
HTT P42858 2/20 0.36
NQO1 P15559 1/20 0.36
SLC22A2 O15244 1/20 0.36
SLC22A1 O15245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16601869 0.94 CYP19A1 (0.40) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL17510056 0.93 CYP19A1 (0.40) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL16601541 0.91 CYP19A1 (0.51) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL16601873 0.84 CYP19A1 (0.46) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL16602199 0.83 CYP19A1 (0.47) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL25937202 0.76 TERT (0.57) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL4399500 0.75 TERT (0.51) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL29637836 0.75 TERT (0.51) CYP19A1MEN1KMT2ABLMTDP1
Iodide SCHEMBL10351792 0.74 TERT (0.53) CYP19A1MEN1KMT2ABLMTDP1
SCHEMBL25937776 0.74 NSD2 (0.58) MEN1KMT2ABLMTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180120231-A1 OPTICAL METHOD FOR DETECTING VIABLE CELLS IN A CELL SAMPLE REAMETRIX INC. 2018-05-03 US disclosed
US-9709500-B2 Optical method for detecting viable microorganisms in a cell sample CHARLES RIVER LABORATORIES, INC. (US) 2017-07-18 US disclosed
US-20150368689-A1 VIABILITY STAINING METHOD JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2015-12-24 US disclosed
US-20150368690-A1 VIABILITY STAINING METHOD JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2015-12-24 US disclosed
US-8993260-B2 Fluorescence-based viability staining method using a membrane permeable flourescent dye and membrane impermeable fluorescence quencher CHARLES RIVER LABORATORIES, INC. (US) 2015-03-31 US disclosed
US-8993259-B2 Method of viability staining with membrane permeable fluorescent dye and membrane impermeable fluorescence quencher CHARLES RIVER LABORATORIES, INC. (US) 2015-03-31 US disclosed