Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16601541 | 0.93 | CYP19A1 (0.51) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL16601869 | 0.92 | CYP19A1 (0.40) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL16602198 | 0.88 | CYP19A1 (0.56) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL16601545 | 0.84 | CYP19A1 (0.44) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL4706929 | 0.83 | CYP19A1 (0.54) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL9619539 | 0.79 | CYP19A1 (0.47) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL17732422 | 0.79 | CYP19A1 (0.73) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL16602199 | 0.79 | CYP19A1 (0.47) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL17510056 | 0.79 | CYP19A1 (0.40) | CYP19A1MAPTPOLBPKMALDH1A1 | |
| SCHEMBL25937202 | 0.78 | TERT (0.57) | CYP19A1MAPTPOLBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993260-B2 | Fluorescence-based viability staining method using a membrane permeable flourescent dye and membrane impermeable fluorescence quencher | CHARLES RIVER LABORATORIES, INC. (US) | 2015-03-31 | — | — | US | disclosed |