Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | CASP7 | P55210 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12516490 | 0.91 | TERT (0.50) | TERTAPPPARP1GPBAR1CYSLTR1 | |
| SCHEMBL12517340 | 0.91 | CCR1 (0.48) | TERTCCR1APPGPBAR1CYSLTR1 | |
| SCHEMBL12516193 | 0.82 | CCR1 (0.47) | TERTCCR1APPGPBAR1CYSLTR1 | |
| SCHEMBL14925257 | 0.78 | PDE10A (0.38) | TERTGPBAR1CYSLTR1ALDH1A1PDE10A | |
| SCHEMBL7833593 | 0.77 | HSD17B10 (0.45) | TERTCCR1APPPARP1GPBAR1 | |
| SCHEMBL12517709 | 0.77 | CCR1 (0.41) | TERTCCR1APPGPBAR1CYSLTR1 | |
| SCHEMBL12517701 | 0.73 | CCR1 (0.38) | TERTCCR1APPCYSLTR1ALDH1A1 | |
| SCHEMBL29970876 | 0.73 | MEN1 (0.46) | TERTPARP1GPBAR1CYSLTR1KDM4E | |
| SCHEMBL16246600 | 0.72 | APP (0.55) | TERTCCR1APPPSMB5 | |
| SCHEMBL7813726 | 0.72 | CYP1A2 (0.46) | CCR1GPBAR1CYSLTR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8993767-B2 | Multiphoton activable quinoline derivatives, their preparation and their uses | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-31 | — | — | US | disclosed |